CONSIDERATIONS TO KNOW ABOUT LEVETIRACETAM VS PHENOBARBITAL

5. Phenytoin, sodium valproate, valproic acid: The effect of phenobarbital on the metabolism of phenytoin appears to become variable. Some investigators report an accelerating effect, although others report no effect. Since the effect of phenobarbital to the metabolism of phenytoin will not be predictable, phenytoin and phenobarbital blood levels r